|
Parameter*
|
CYC (n = 25)
|
MMF (n = 25)
|
Between-group p value (baseline)
|
Between-group p value (6 months)
|
|---|
|
Baseline
|
6 months
|
p value
|
Baseline
|
6 months
|
p value
|
|---|
|
LH (IU/ml)
|
5.8 ± 3.6
|
17.6 ± 38.4
|
0.13
|
9.4 ± 7.7
|
8.3 ± 5.6
|
0.55
|
0.065
|
0.55
|
|
FSH (IU/ml)
|
5.2 ± 3.4
|
25.1 ± 46.0
|
0.03
|
4.8 ± 1.8
|
6.1 ± 3.1
|
0.07
|
0.938
|
0.36
|
|
E2 (pg/ml)
|
80.2 ± 57.6
|
56.1 ± 52.3
|
0.13
|
89.6 ± 67.3
|
113.0 ± 73.3
|
0.25
|
0.749
|
< 0.001
|
|
AMH (ng/ml)
|
5.7 ± 6.7
|
1.2 ± 1.7
|
0.002
|
6.3 ± 3.9
|
5.8 ± 5.6
|
0.71
|
0.061
|
< 0.001
|
|
Inhibin B (pg/ml)
|
56.1 ± 21.9
|
16.5 ± 18.0
|
< 0.001
|
53.1 ± 24.7
|
82.9 ± 37.7
|
0.002
|
0.547
|
< 0.001
|
|
Ovarian volume (cm3)
|
29.3 ± 15.8
|
17.9 ± 13.7
|
0.005
|
25.7 ± 20.4
|
26.1 ± 11.1
|
0.92
|
0.49
|
0.02
|
|
Antral follicular count
|
6.4 ± 2.4
|
5.5 ± 4.2
|
0.32
|
6.7 ± 2.5
|
8.0 ± 3.0
|
0.07
|
0.74
|
0.02
|
- LH luteinizing hormone, FSH follicle-stimulating hormone, E2 estradiol, AMH anti-Mullerian hormone, CYC cyclophosphamide, MMF mycophenolate mofetil *Reported as mean ± SD
