Fig. 3

S100A9^−/− mice show less pain behavior than WT mice in SCW synovitis. a Wt mice showed a dip in the loading of the right, affected limb, while S100a9^−/− mice did not. Although the stand phase of WT mice was not different in the affected right hind limbs from controls, all other limbs showed an increased stance (b). Particularly at the end of each stand of the affected joints, the left limb was used to unload the right hind limb, as reflected in the TDS (c) in WT but not S100A9^−/− mice. Found in two separate experiments (n = 8 each). Two-way ANOVA with a Tukey post hoc test (*p < 0.05; **p < 0.01; ***p < 0.001)