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Table 4 Comparison of changes in total and HMW adiponectin between non-responders, moderate responders and good responders (EULAR definition) at each time point (results are given as mean ± SD; N number of subjects; P#: Kruskal Wallis test. Results of post hoc analysis [Dwass-Steel-Crichtlow-Fligner test] for total adiponectin at M1: moderate versus good responders: p = 0.0482; non-responders versus good responders: p = 0.974)

From: Increased high molecular weight adiponectin and lean mass during tocilizumab treatment in patients with rheumatoid arthritis: a 12-month multicentre study

 

Adiponectin (훍g/mL)

Non-responders

Moderate responders

Good responders

P#

M1

Total

0.28 ± 3.4 (28)

2.41 ± 3.2 (41)

0.15 ± 3.8 (24)

0.012

HMW

0.53 ± 1.6 (27)

1.49 ± 3 (41)

0.82 ± 1.7 (24)

0.6

M3

Total

1.55 ± 3.4 (15)

1.9 ± 5.7 (31)

0.78 ± 4.3 (44)

0.9

HMW

1.55 ± 3.4 (15)

1.9 ± 5.7 (31)

0.78 ± 4.3 (44)

0.9

M6

Total

− 0.87 ± 2.9 (17)

1.9 ± 3.3 (15)

1.17 ± 4.7 (52

0.078

HMW

− 0.87 ± 2.9 (17)

1.9 ± 3.3 (15)

1.17 ± 4.7 (52

0.078

M12

Total

3.1 ± 6.9 (4)

- 0.06 ± 4.5 (14)

0.77 ± 5.1 (46)

0.48

HMW

0.78 ± 1.9 (4)

- 0.05 ± 2.1 (14)

0.53 ± 1.6 (47)

0.42