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Table 2 Total effect of E-DII on incident ROA and incident SxOA

From: Inflammatory potential of diet and risk of incident knee osteoarthritis: a prospective cohort study

E-DII in quartile Q1 Q2 Q3 Q4 P for trend*
ROA
 Median − 3.9 − 2.7 − 1.3 0.9  
 ROA knees# 48/896 53/892 66/892 65/892  
 Model 1 1.00 (ref) 1.12 (0.75, 1.68) 1.48 (1.00, 2.18) 1.43 (0.96, 2.11) 0.049
 Model 2 1.00 (ref) 1.27 (0.84, 1.94) 1.53 (1.01, 2.32) 1.73 (1.15, 2.62) 0.007
SxOA
 Median − 3.9 − 2.7 − 1.4 0.8  
 SxOA knees# 218/1472 237/1470 260/1470 263/1468  
 Model 1 1.00 (ref) 1.12 (0.92, 1.37) 1.28 (1.05, 1.56) 1.37 (1.12, 1.68) 0.001
 Model 2 1.00 (ref) 1.13 (0.92, 1.40) 1.27 (1.04, 1.56) 1.43 (1.16, 1.76) 0.001
  1. E-DII energy-adjusted dietary inflammatory index, BMI body mass index, OA osteoarthritis, PASE Physical Activity in the Elderly Scale, ROA radiographic knee osteoarthritis, SxOA, symptomatic knee osteoarthritis
  2. *Test for trend based on the variable containing the median value for each quartile
  3. #Number of OA affected/total number of knees in each quartile of the dietary inflammatory index
  4. Model 1 adjusted for age (years), sex (men vs women), race (white vs non-white), and total energy intake (kcal/day)
  5. Model 2 further adjusted for education (< college vs ≥ college), yearly income level (< 50,000 US$ vs ≥ 50,000 US$), tobacco use (non-smoker vs smoker), and physical activity (PASE, continuous)
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