Skip to main content

Table 2 Meta-analysis for GDF5 rs143383 polymorphisms and knee osteoarthritis risk

From: Association between growth differentiation factor 5 rs143383 genetic polymorphism and the risk of knee osteoarthritis among Caucasian but not Asian: a meta-analysis

Variables N C vs T CC+CT vs TT CC vs CT+TT CC vs TT CT vs CC+TT
   OR (95% CI) Ph OR (95% CI) Ph OR (95% CI) Ph OR (95% CI) Ph OR (95% CI) Ph
Total 20 0.836 1 × 10−4 0.80 1 × 10−4 0.79 0.001 0.88 0.002 0.88 0.002
   (0.76–0.91)   (0.72–0.90)   (0.68–0.92)   (0.80–0.97)   (0.80–0.96)  
Ethnicity
 Asian 8 0.84 1 × 10−4 0.80 1 × 10−4 0.76 0.002 0.85 0.011 0.85 0.011
   (0.67–1.02)   (0.63–1.00)   (0.50–1.12)   (0.72–1.00)   (0.72–1.00)  
 Caucasian 12 0.84 0.12 0.81 1 × 10−4 0.81 0.92 0.90 0.013 0.89 0.016
   (0.79–0.91)   (0.71–0.92)   (0.72–0.90)   (0.80–1.02)   (0.79–1.02)  
  1. N number of studies
  2. Ph value of Q-test for heterogeneity test. Random-effects model was used when p value for heterogeneity test < 0.05; otherwise, fix-effects model was used