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Table 1 Baseline characteristics of patients included in the PEARL study

From: Effects of disease activity on lipoprotein levels in patients with early arthritis: can oxidized LDL cholesterol explain the lipid paradox theory?

 

Total population (N = 448)

oxLDL not studied (N = 281)

oxLDL studied (N = 167)

p

Female gender (%)

354 (79)

224 (79.7)

130 (77.8)

0.638

Age (years)

55 [44–67]

58 [44–68]

52 [43–65]

0.08

Disease duration (months)

5 [3–8]

5 [3–8]

6 [4–9]

0.004

DAS28

4.4 [3.3–5.5]

4.1 [3.3–5.5]

4.7 [3.5–5.7]

0.060

SDAI

18 [9.6–29.2]

17 [8.8–29]

19.2 [10.4–29.5]

0.183

HUPI

7 [4.5–10]

7 [4–10]

8 [5–9.5]

0.174

HAQ

0.875

0.875

1

0.059

[0.5–1.625]

[0.375–1.625]

[0.625–1.625]

 

RF (%)

54

57

48

0.054

ACPA (%)

50

53

46

0.175

UA (%)

28

26

30

0.297

Smoking (%)

21.4

20

24.2

0.36

Statins use (%)

10.7

12

9

0.361

BMI p50 [IQR]

26.1 [23.4–29]

25.9 [22.9–29]

26.3 [23.9–29.1]

0.171

  1. Significance was considered if p <  0.05. In bold significant p values
  2. Abbreviations: ACPA anti-citrullinated protein antibodies, BMI body mass index, DAS28 Disease Activity Score (28 joints count), HAQ Health Assessment Questionnaire, HUPI Hospital Universitario La Princesa Index, IQR interquartile range, N number, oxLDL oxidized LDL cholesterol, p p value, PEARL Princesa Early Arthritis Register Longitudinal, RF rheumatoid factor, SDAI Simplified Disease Activity Index, UA undifferentiated arthritis