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Table 1 Baseline characteristics of patients included in the PEARL study

From: Effects of disease activity on lipoprotein levels in patients with early arthritis: can oxidized LDL cholesterol explain the lipid paradox theory?

  Total population (N = 448) oxLDL not studied (N = 281) oxLDL studied (N = 167) p
Female gender (%) 354 (79) 224 (79.7) 130 (77.8) 0.638
Age (years) 55 [44–67] 58 [44–68] 52 [43–65] 0.08
Disease duration (months) 5 [3–8] 5 [3–8] 6 [4–9] 0.004
DAS28 4.4 [3.3–5.5] 4.1 [3.3–5.5] 4.7 [3.5–5.7] 0.060
SDAI 18 [9.6–29.2] 17 [8.8–29] 19.2 [10.4–29.5] 0.183
HUPI 7 [4.5–10] 7 [4–10] 8 [5–9.5] 0.174
HAQ 0.875 0.875 1 0.059
[0.5–1.625] [0.375–1.625] [0.625–1.625]  
RF (%) 54 57 48 0.054
ACPA (%) 50 53 46 0.175
UA (%) 28 26 30 0.297
Smoking (%) 21.4 20 24.2 0.36
Statins use (%) 10.7 12 9 0.361
BMI p50 [IQR] 26.1 [23.4–29] 25.9 [22.9–29] 26.3 [23.9–29.1] 0.171
  1. Significance was considered if p <  0.05. In bold significant p values
  2. Abbreviations: ACPA anti-citrullinated protein antibodies, BMI body mass index, DAS28 Disease Activity Score (28 joints count), HAQ Health Assessment Questionnaire, HUPI Hospital Universitario La Princesa Index, IQR interquartile range, N number, oxLDL oxidized LDL cholesterol, p p value, PEARL Princesa Early Arthritis Register Longitudinal, RF rheumatoid factor, SDAI Simplified Disease Activity Index, UA undifferentiated arthritis