Table 2 Variables that have an influence on lipid profile of patients with early arthritis
Total cholesterol (mg/dl) | HDL cholesterol (mg/dl) | LDL cholesterol (mg/dl) | oxLDL (sqrt U/ml) | |||||
|---|---|---|---|---|---|---|---|---|
β coeff. ± s.e. | p | β coeff. ± s.e. | p | β coeff. ± s.e. | p | β coeff. ± s.e. | p | |
Gender | ||||||||
Male | Ref. | – | Ref. | – | n.i. | – | Ref. | – |
Female | 10.5 ± 3.4 | 0.002 | 12.4 ± 1.9 | < 0.001 | −1.03 ± 0.48 | 0.031 | ||
Age | ||||||||
< 45 years | Ref. | – | Ref. | – | Ref. | – | n.i. | |
45–65 years | 23.1 ± 3.3 | < 0.001 | 1.9 ± 1.9 | 0.319 | 16.4 ± 3.3 | < 0.001 | ||
> 65 years | 23.9 ± 3.7 | < 0.001 | 5.6 ± 2.1 | 0.008 | 12.3 ± 3.7 | 0.001 | ||
BMI | 0.68 ± 0.29 | 0.019 | −0.62 ± 0.16 | < 0.001 | 0.71 ± 0.29 | 0.016 | n.i. | |
DA | ||||||||
Remission | Ref. | – | Ref. | – | Ref. | – | Ref. | – |
Low | 2.19 ± 1.74 | 0.582 | −0.79 ± 1.04 | 0.442 | 1.96 ± 2.13 | 0.359 | 0.28 ± 0.48 | 0.564 |
Moderate | −3.04 ± 1.90 | 0.110 | −3.30 ± 1.14 | 0.004 | 1.35 ± 2.30 | 0.556 | 0.43 ± 0.48 | 0.367 |
High | −14.95 ± 2.53 | < 0.001 | −8.89 ± 1.56 | < 0.001 | −6.39 ± 2.92 | 0.029 | 1.88 ± 0.66 | 0.004 |
Statins | −27.4 ± 3.05 | < 0.001 | n.i. | − 28.7 ± 3.2 | < 0.001 | n.i. | ||
Smoking | n.i. | n.i. | 7.0 ± 4.5 | 0.118 | n.i. | |||
MTX (mg/wk) | n.i. | 2.06 ± 0.94 | 0.029 | n.i. | n.i. | |||
Leflunomide (mg/d) | 6.4 ± 2.2 | 0.003 | 2.35 ± 1.27 | 0.064 | 4.79 ± 2.57 | 0.062 | n.i. | |
Abatacept (Y/N) | 36.94 ± 16.01 | 0.021 | 40.54 ± 9.57 | < 0.001 | n.i. | n.i. | ||
TNF i (Y/N) | n.i. | n.i. | n.i. | 1.597 ± 1.003 | 0.111 | |||
LDL (mg/dl) | n.i. | n.i. | n.i. | 0.015 ± 0.005 | 0.005 | |||
Frozen storage (months) | n.i. | n.i. | n.i. | −0.003 ± 0.001 | < 0.001 | |||