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Table 1 Baseline characteristics of the present patients (n = 24)

From: Long-term changes in renal function after treatment initiation and the importance of early diagnosis in maintaining renal function among IgG4-related tubulointerstitial nephritis patients in Japan

 

CKD stage 3

CKD stage 4

CKD stage 5

n (%)

10 (41.7)

7 (29.2)

7 (29.2)

Continuous variables, mean (SD)

Age, years

64.3 (11.1)

69.9 (8.4)

73.7 (6.4)

Cr, mg/dL

1.35 (0.22)

2.67 (0.61)

6.39 (2.22)

eGFR, mL/min/1.73m2

42.8 (9.8)

19.7 (3.7)

8.2 (3.5)

IgG, mg/dL (reference range, 870–1700 mg/dL)

4424.9 (1387.9)

4216.1 (1215.9)

3304.1 (685.6)

IgG4, mg/dL (reference range, 5–105 mg/dL)

1706.1 (1360.8)

659.5 (433.4)

505.2 (467.5)

IgG4/IgG ratio

0.38 (0.19)

0.18 (0.12)

0.14 (0.11)

C3, mg/dL (reference range, 63–134 mg/dL)

55.2 (37.2)

36.0 (19.8)

44.9 (33.3)

C4, mg/dL (reference range, 13–36 mg/dL)

12.0 (14.6)

1.8 (0.9)

6.4 (6.5)

Categorical variables, n (%)

Gender, male

8 (80.0)

6 (85.7)

6 (85.7)

Proteinuria

  (−)

4 (40.0)

0 (0.0)

1 (14.3)

  (±)

3 (30.0)

2 (28.6)

0 (0.0)

  (1+)

3 (30.0)

5 (71.4)

5 (71.4)

  (2+)

0 (0.0)

0 (0.0)

1 (14.3)

  g/gCr

0.27 (0.24)

0.67 (0.63)

0.67 (0.19)

Hematuria

  (−)

7 (70.0)

4 (57.1)

3 (42.9)

  (±)

1 (10.0)

2 (28.6)

1 (14.3)

  (1+)

1 (10.0)

0 (0.0)

3 (42.9)

  (2+)

1 (10.0)

1 (14.3)

0 (0.0)

Histological main stage

  Stage A

5 (50.0)

1 (14.3)

0 (0.0)

  Stage B

3 (30.0)

6 (85.7)

6 (85.7)

  Stage C

2 (20.0)

0 (0.0)

1 (14.3)

  1. Abbreviations: CKD chronic kidney disease, Cr creatinine, eGFR estimated glomerular filtration rate