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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP

Fig. 2

Overexpression of miR-431-5p suppressed cell proliferation in RA FLSs. a qRT-PCR for the relative expression of miR-431-5p in HFLS-RA cells transfected with miR-431-5p mimics or inhibitor. b Cell proliferation pattern of HFLS-RA cells transfected with miR-431-5p mimics or inhibitor for 0 h, 24 h, 48 h, 72 h, and 96 h using the CCK-8 assay. c, d Cell proliferation of HFLS-RA cells transfected with miR-431-5p mimics or inhibitor for 48 h by EdU staining assay. Each experiment was performed independently in triplicates. *P < 0.05, ***P < 0.001, ****P < 0.0001, compared with the NC groups

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