Skip to main content
Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP

Fig. 5

miR-431-5p regulated cell proliferation via XIAP in RA FLSs. a qRT-PCR for the relative expression of XIAP in HFLS-RA cells transfected with three siRNAs targeting XIAP. b, c Western blotting to determine the levels of XIAP in HFLS-RA cells transfected with three siRNAs against XIAP. d Proliferation of HFLS-RA cells transfected with miR-431-5p inhibitor and/or siRNAs against XIAP for 0 h, 24 h, 48 h, 72 h, and 96 h using CCK-8 assay. Asterisk for siRNA#1 and pound sign for siRNA#2. e, f Proliferation of HFLS-RA cells transfected with miR-431-5p inhibitor and/or siRNAs against XIAP for 48 h using EdU staining assay. Each experiment was performed independently in triplicates. *P < 0.05, ****P < 0.0001, compared with the NC groups

Back to article page