Table 2 Univariate Cox regression analysis of factors influencing risk of death in patients with ≥ 1 HAQ-DI measurement

Male gender

1.15

0.57, 2.35

0.698

HAQ-DI score

3.01

1.98, 4.60

< 0.001

Age at onset of RP

1.03

1.00, 1.05

0.030

mRSS

1.02

0.99, 1.05

0.303

RNA polymerase III positive

0.04

0.00, 11.11

0.260

Anti-topoisomerase I antibody

0.92

0.45, 1.88

0.817

Immunomodulator treatment

0.86

0.45, 1.63

0.638

Corticosteroids > 10 mg/day

6.29

2.64, 14.98

< 0.001

One advanced organ involvement

3.93

1.99, 7.78

< 0.001

Two advanced organ involvement

8.43

3.40, 20.91

< 0.001

Advanced lung involvement

4.81

2.37, 9.77

< 0.001

Advanced cardiac involvement

6.24

1.47, 26.50

0.013

Advanced GI involvement

2.22

1.06, 4.64

0.035

Advanced PH involvement

6.50

2.66, 15.88

< 0.001

Advanced renal involvement

1.12

0.15, 8.13

0.914