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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes

Fig. 1

Levels of BMP-2, -4, and -7 in synovial fluids from patients with peripheral spondyloarthritis (SpA), compared to osteoarthritic (OA) patients. a BMP-2, BMP-4, and BMP-7 contents were measured by ELISA. b BMP-2/BMP-4 ratio was calculated to illustrate the equilibrium between the two growth factors. *Statistical difference between the n = 56 SpA and n = 21 OA samples. Among SpA patients, BMP-2/BMP-4 ratio was compared between HLAB27-positive and -negative status (c), and patients treated (+) or not (−) with NSAIDs, corticosteroids (Cort), DMARDs, or anti-TNF-α biotherapies (d). Symbols represent individual data points; the stick band represents the mean of each group

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