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Table 2 Correlation analysis between inflammatory markers and BMP-2 levels and BMP-2/BMP-4 ratios in SF of SpA patients

From: Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes

 

n

OPG

CRP

TNF-α

IL-6

IL-17

21

33

21

21

21

Mean ± SEM

46.0 ± 10.4 ng/mL

58.0 ± 10.4 pg/mL

22.5 ± 3.6 ng/mL

44.9 ± 12.0 pg/mL

32.9 ± 14.3 pg/mL

BMP-2 levels

R2

0.395#

0.264#

0.179

0.175

0.075Ɨ

p value

0.002*

0.002*

0.056

0.060

BMP-2/BMP-4 ratio

R2

0.551#

0.041

0.225#

0.196

0.018Ɨ*

p value

0.0001*

0.260

0.030*

0.044*

  1. *Significant p values
  2. #R2 > 0.2
  3. ƗNon-parametric statistical analysis using the Spearman test