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Table 4 Top 10 differentially expressed genes comparing paired frozen media (CryoStor® CS10) compared to fresh media (RPMI) skin samples. Full 123 DEGs are in Supplement

From: Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma

 

Average log fold change

p value

% of cells in PCA 1

% of cells in PCA 2

Adjusted p value

KRTDAP

− 1.08932

< 0.0001

0.053

0.302

< 0.0001

DSC3

− 0.53179

< 0.0001

0.06

0.295

< 0.0001

S100A14

− 0.70139

< 0.0001

0.086

0.33

< 0.0001

PERP

− 1.00375

< 0.0001

0.4

0.635

< 0.0001

DSP

− 0.89602

< 0.0001

0.13

0.381

< 0.0001

SERPINB2

− 0.5951

< 0.0001

0.026

0.23

< 0.0001

AQP3

− 0.83687

< 0.0001

0.145

0.388

< 0.0001

LY6D

− 0.72067

< 0.0001

0.08

0.319

< 0.0001

SERPINB5

− 0.45845

< 0.0001

0.054

0.273

< 0.0001

KRT2

− 1.12371

< 0.0001

0.017

0.206

< 0.0001