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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Empirical evidence of disease activity thresholds used to indicate need for major therapeutic change in US veterans with rheumatoid arthritis

Fig. 1

Youden Index and empirical thresholds. ROC curves of disease activity measure thresholds for the likelihood to initiate MTC and empiric thresholds are shown. Empirical optimal thresholds with 95% CI, Youden indices, sensitivity and specificity at each threshold, and the AUC for the ROC curves are reported in the table. 95% CI, 95% confidence interval; AUC, area under the curve; DAS28, Disease Activity Score for 28 joints; CDAI, Clinical Disease Activity Index; MTC, major therapeutic change; ROC, receiver operating characteristic curves; RAPID3, Routine Assessment of Patient Index Data 3

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