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Table 1 Characteristics in AAV patients and controls

From: Association of TERT and DSP variants with microscopic polyangiitis and myeloperoxidase-ANCA positive vasculitis in a Japanese population: a genetic association study

Characteristics

Groups

Number

Female/male

AAV

 EMA classification

MPA

315

192/123

GPA

119

67/52

EGPA

73

46/27

Unclassifiable

37

24/13

 ANCA specificity

MPO-AAV

432

268/164

PR3-AAV

67

33/34

 Presence/absence of ILD in MPO-AAVa

MPO-AAV-ILD

176

101/75

MPO-AAV-noILD

216

139/77

Controls

HCb

785

478/307

4.7KJPNc

4773

2641/2130

  1. AAV ANCA-associated vasculitis, EMA European Medicines Agency, MPA microscopic polyangiitis, GPA granulomatosis with polyangiitis, EGPA eosinophilic granulomatosis with polyangiitis, MPO-AAV myeloperoxidase (MPO)-ANCA positive AAV, PR3-AAV proteinase 3 (PR3)-ANCA positive AAV, ILD interstitial lung disease, MPO-AAV-ILD MPO-AAV with ILD, MPO-AAV-noILD MPO-AAV without ILD
  2. aInformation of ILD was not available for 40 patients with MPO-AAV
  3. bHealthy controls recruited by our research group
  4. cAllele frequency data in 4.7KJPN was obtained from the Japanese Multi Omics Reference Panel (jMorp) [22, 23]