Fig. 3

IL-6 production and citrullinated protein levels in intestines and serum. To evaluate intestinal inflammation, IL-6 production in intestinal tissue and serum was measured by ELISA (a small intestine, b large intestine). To assess CP synthesis, ELISA was performed (c–f). Data represent mean ± SD (a–f) of 6 mice per group. Statistical analyses were performed using the Tukey-Kramer test and Bonferroni-corrected Mann-Whitney U test for multiple comparisons (*P < 0.05, **P < 0.01)