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Table 3 Body weight, BMI and measures of disease activity and function before weight loss treatment at baseline (BL) and after 12-months (M12) and 24-months (M24) in patients with psoriatic arthritis (PsA). Values are median and inter-quartile range (IQR)

From: Weight loss is associated with sustained improvement of disease activity and cardiovascular risk factors in patients with psoriatic arthritis and obesity: a prospective intervention study with two years of follow-up

  BL
N = 39
M12
N = 39
M24
N = 35
BL vs M12
p-value
N = 39
BL vs M24
p-value
N = 35
Body weight kg 106.0 (93.5–112.5) 87.5 (80.6–95.5) 92.7 (85.7–100.7) < 0.001 < 0.001
BMI kg/m2 35.2 (33.9–37.9) 30.5 (28.0–32.9) 32.3 (30.3–35.4) < 0.001 < 0.001
Tender joints 68 count 4 (1–14) 3 (0–6) 2 (0–7) 0.001 < 0.001
Swollen joints 66 count 0 (0–1) 0 (0–1) 0 (0–0) 0.015 0.003
Leeds enthesitis index, count 1 (0–4) 0 (0–2) 1 (0–3) < 0.001 0.002
BSA % 0.75 (0–2) 0.25 (0–1) 0.25 (0–1.5) 0.018 0.194
CRP mg/L 5 (3–9) 2 (1–5) 3 (2–5) 0.009 0.011
Hb g/L 144 (131–150) 143 (131–150) 142 (135–149) 0.296 0.537
WBC 109/L 6.1 (5.3–7.7) 5.7 (5.0–7.4) 5.9 (4.7–7.8) 0.133 0.346
PLT 109/L 270 (202–299) 262 (203–308) 273 (220–332) 0.368 0.334
VAS Pain mm 35 (15–60) 30 (14–46) 35 (15–55) 0.073 0.799
VAS Global health, mm 40 (20–70) 30 (17–52) 40 (20–60) 0.023 0.282
VAS Fatigue mm 50 (30–70) 30 (20–60) 60 (30–80) 0.021 0.064
HAQ score 0.63 (0.13–1.00) 0.25 (0–0.63) 0.25 (0.13–0.88) 0.002 0.033
BASFI score 2.6 (1.4–5.2) 1.6 (0.57–3.6) 2.1 (0.9–4.2) < 0.001 0.131
DLQI score 1 (0–4) 1 (0–4) 1 (0–4) 0.380 0.982
DAS-28CRP score 3.1 (2.1–3.7) 2.4 (1.8–3.3) 2.4 (1.7–2.9) < 0.001 < 0.001
DAPSA score 16.1 (6.2–23.3) 9.5 (4.8–18.1) 9.7 (5.3–19.0) < 0.001 < 0.001
MDA n (%) 11 (28.2) 15 (38.5) 16 (45.7) 0.008 0.016
  1. BASFI = Bath Ankylosing Spondylitis Functional Index, BMI = Body Mass Index, BSA = Body Surface Area, CRP = C- reactive protein, DAPSA = Disease Activity in PSoriatic Arthritis, DAS28CRP = Disease Activity Score using 28 joint counts based on CRP, DLQI = Dermatology Life Quality Index, ESR = erythrocyte sedimentation rate, HAQ = Health Assessment Questionnaire, Hb = hemoglobin, MDA = Minimal Disease Activity, PLT = platelet count, VAS = Visual Analogue Scale, WBC = White Blood Cell count