Fig. 1
From: Heparan sulfate functions are altered in the osteoarthritic cartilage
Quantification of sulfated GAG. The amounts of total sulfated GAG (a) and isolated CS (b), HS (c), and KS (d) were normalized in μg of GAG per mg of articular cartilage from healthy control donors (CT, n = 7) and osteoarthritis patients (OA, n = 11). The values of the CT group were compared to the values obtained for the femur (F), tibial plateau (TP), and patella (P) samples from OA patients and to the mean of the 3 samples from each OA patient (OA). The value of a GAG sample was the mean of 3 values obtained from 3 independent experiments. All values per group are expressed as a mean ± SEM. P values were calculated using an ordinary one-way ANOVA test followed by pairwise comparisons using the Dunnett test: *< 0.05, **< 0.01, ***< 0.001, ****< 0.0001. e Distribution of HS, KS, and CS amounts as a percentage of the amount of total GAG (100%)