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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Derivation and internal validation of a multi-biomarker-based cardiovascular disease risk prediction score for rheumatoid arthritis patients

Fig. 2

Goodness of fit: Predicted CVD risk versus observed 3-year CVD event rates. The observed 3-year CVD event rate was determined for each event-based decile and is shown vs. the average predicted 3-year risk in each decile. Analysis used the validation dataset (N = 10,275). Observed event rates were determined as Kaplan-Meier (95% log-log CI) estimates. P = 0.39 by the Greenwood-Nam-D’Agostino test, indicating good fit. CVD event is myocardial infarction, stroke, or CV death. 3-year CVD risk categories (low, borderline, intermediate, high) were derived from the 10-year risk categories of the 2018 Guidelines of the American College of Cardiology/American Heart Association [8]. Threshold between low and borderline risk categories is 1.3% (not shown). CI confidence interval, CVD cardiovascular disease, MBDA multi-biomarker disease activity

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Arthritis Research & Therapy

ISSN: 1478-6362

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