Fig. 4

Contribution to CVD risk prediction by MBDA-based CVD risk score and clinical models. Likelihood ratio test statistics are shown for univariable (i.e., single-score) analyses of a CVD risk prediction by the MBDA-based CVD risk score and four comparison models, using the validation dataset (N = 10,275) (see also Table 3). P values are by the likelihood ratio test. The clinical model includes age, sex, tobacco use, diabetes, hypertension, and history of CVD. CRP C-reactive protein, CVD cardiovascular disease, MBDA multi-biomarker disease activity