Table 3 Contribution of MBDA-based CVD risk score and other models to prediction of 3-year CVD risk
CVD risk prediction score | Single-score analyses (univariable) | Sequential analyses of paired scores (bivariable) | |||||||
|---|---|---|---|---|---|---|---|---|---|
A. Non-MBDA-based CVD Risk Score added to a base model of MBDA-based CVD Risk Score | B. MBDA-based CVD Risk Score added to a non-MBDA-based CVD Risk Score base model | ||||||||
HR (95% CI) | LRT statistic | p value | HR (95% CI) | Increment in LRT statistic | p value | HR (95% CI) | Increment in LRT statistic | p value | |
Age + sex | 3.44 (2.62–4.53) | 82.2 | 1.22 × 10−19 | 1.34 (0.96–1.86) | 3.0 | 0.084 | 2.62 (2.14–3.20) | 83.3 | 7.15 × 10−20 |
Age + sex + CRP | 2.97 (2.38–3.70) | 95.8 | 1.29 × 10−22 | 1.13 (0.84–1.54) | 0.7 | 0.412 | 2.71 (2.15–3.41) | 67.4 | 2.20 × 10− 16 |
Clinical | 3.08 (2.50–3.80) | 115.1 | 7.34 × 10−27 | 1.24 (0.89–1.71) | 1.7 | 0.197 | 2.56 (1.98–3.29) | 49.0 | 2.51 × 10−12 |
Clinical + CRP | 2.94 (2.43–3.55) | 127.5 | 1.44 × 10−29 | 1.12 (0.79–1.60) | 0.4 | 0.526 | 2.67 (1.96–3.63) | 35.4 | 2.67 × 10−9 |
MBDA-based CVD risk score | 2.89 (2.46–3.41) | 162.5 | 4.67 × 10−38 | – | – | – | – | – | – |