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Table 2 Clinical manifestations of cryoglobulinaemic vasculitis in all patients

From: IgG subclasses in cryoglobulins: link to composition and clinical manifestations

Patients

Total

Type I CG

Mixed

Type II CG

Type III CG

P

n = 86

n = 10

n = 76

n = 50

n = 26

Asymptomatic patients, n (%)

22 (25.6)

0 (0)

22 (28.9)

9 (18)

13 (50)

0.06§/0.007§§

Symptomatic patients, n (%)

64 (74.4)

10 (100)

54 (71.1)

41 (82)

13 (50)

 

Clinical manifestations:

 Cutaneous

38 (59.4)

7 (70)

31 (40.8)

24 (48)

7 (26.9)

0.10§/0.09§§

 Neurological

29 (45.3)

4 (40)

25 (32.9)

19 (38)

6 (23.1)

0.73§/0.21§§

 Renal

20 (31.2)

4 (40)

16 (21)

13 (26)

3 (11.5)

0.23§/0.23§§

 Rheumatological

18 (28.1)

2 (20)

16 (21)

12 (24)

4 (15.4)

0.99§/0.55§§

 Digestive

10 (15.6)

2 (20)

8 (10.5)

3 (6)

5 (19.2)

0.33§/0.11§§

  1. Cutaneous signs: Raynaud phenomenon/acrocyanosis, livedo, purpura, ulcers; Neurological signs: peripheral neuropathy; Renal signs: glomerulonephritis, haematuria, proteinuria; Rheumatological signs: arthralgia, arthritis, myalgia; Digestive signs: intestinal pain
  2. n number of patients, % percentage/number of patients of each column, Mixed column type II and type III CG
  3. §Comparison between type I and mixed CG
  4. §§Comparison between type II and type III CG