From: IgG subclasses in cryoglobulins: link to composition and clinical manifestations
Patients | Total | Type I CG | Mixed | Type II CG | Type III CG | P |
---|---|---|---|---|---|---|
n = 86 | n = 10 | n = 76 | n = 50 | n = 26 | ||
Asymptomatic patients, n (%) | 22 (25.6) | 0 (0) | 22 (28.9) | 9 (18) | 13 (50) | 0.06§/0.007§§ |
Symptomatic patients, n (%) | 64 (74.4) | 10 (100) | 54 (71.1) | 41 (82) | 13 (50) | |
Clinical manifestations: | ||||||
Cutaneous | 38 (59.4) | 7 (70) | 31 (40.8) | 24 (48) | 7 (26.9) | 0.10§/0.09§§ |
Neurological | 29 (45.3) | 4 (40) | 25 (32.9) | 19 (38) | 6 (23.1) | 0.73§/0.21§§ |
Renal | 20 (31.2) | 4 (40) | 16 (21) | 13 (26) | 3 (11.5) | 0.23§/0.23§§ |
Rheumatological | 18 (28.1) | 2 (20) | 16 (21) | 12 (24) | 4 (15.4) | 0.99§/0.55§§ |
Digestive | 10 (15.6) | 2 (20) | 8 (10.5) | 3 (6) | 5 (19.2) | 0.33§/0.11§§ |