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Table 1 The demographic data, BVAS and VDI scores, laboratory test results, and Doppler image results of 428 patients with Takayasu's arteritis at baseline

From: Association between acute phase reactants, interleukin-6, tumor necrosis factor-α, and disease activity in Takayasu’s arteritis patients

  Total (n = 428) Active group (n = 188) Inactive group (n = 240) p value
Age, years 31.8 ± 9.5 31.8 ± 9.9 31.8 ± 9.1 0.26
Female, n (%) 393 (91.8) 174 (92.6) 219 (91.3) 0.63
Disease duration, months (Q1, Q3) 53 (29, 99) 52 (29, 107) 54 (31, 96) 0.51
Median follow-up time, months (Q1, Q3)# 49 (28, 85) 33 (25, 61) 64 (34, 98) < 0.001
BVAS scores 6.7 ± 3.7 7.0 ± 3.7 6.4 ± 3.7 0.10
VDI scores 2.7 ± 1.8 2.8 ± 2.0 2.6 ± 1.6 0.28
Laboratory test results
 ESR, mm/1st hour 17.1 ± 19.6 25.6 ± 25.1 10.4 ± 9.4 < 0.001
 ESR > 20 mm/1st hour, n (%) 106/421* (25.2) 78/186* (41.9) 28/235* (11.9) < 0.001
 hsCRP, mg/L 13.2 ± 26.7 25.6 ± 36.2 3.4 ± 5.5 < 0.001
 hsCRP > 8 mg/L, n (%) 141/410* (34.4) 115/181* (63.5) 26/229* (11.4) < 0.001
 IL-6, pg/ml 13.9 ± 40.0 21.2 ± 42.3 7.4 ± 36.7 0.003
 IL-6 > 5.9 pg/ml, n (%) 82/241* (34.0) 64/114* (56.1) 18/127* (14.2) < 0.001
 TNFα, pg/ml 16.3 ± 34.2 19.9 ± 44.3 13.0 ± 21.3 0.02
 TNFα > 8.1 pg/ml, n (%) 104/238* (43.7) 54/112* (48.2) 50/126* (39.7) 0.19
Repeated vascular Doppler image results compared to former results
 Stable 175 (40.1%) 27 (14.4%) 148 (61.7%)  
 Improved 15 (3.5%) 2 (1.1%) 13 (5.4%)  
 Progressed 238 (55.6%) 159 (84.6%) 79 (32.9%)  
  1. Abbreviation: ESR erythrocyte sedimentation rate, hsCRP high sensitive C-reactive protein, IL-6 interleukin-6, TNFα tumor necrosis factor-α
  2. #Among the follow-up patients
  3. *Actually detected