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Table 2 Association between ESR, hsCRP, IL-6 and TNFα with disease activity at baseline in logistic regression. Results of univariate logistic regression analysis were shown in this table, which analyzed the association between ESR, hsCRP, IL-6 and TNFα with disease activity at baseline in 428 patients

From: Association between acute phase reactants, interleukin-6, tumor necrosis factor-α, and disease activity in Takayasu’s arteritis patients

  Odds ratio (95% CI) p value Sensitivity (95% CI) Specificity (95% CI)
ESR (> 20 mm/1st hour) 5.34 (3.27 ~ 8.72) < 0.001 41.9% (34.8%–49.4%) 88.1% (83.2%–91.9%)
hsCRP (> 8 mg/L) 13.60 (8.18 ~ 22.62) < 0.001 63.5% (56.1%–70.6%) 88.7% (83.8%–92.5%)
IL-6 (> 5.9 pg/ml) 7.75 (4.17 ~ 14.42) < 0.001 56.1% (46.5%–65.4%) 85.8% (78.5%–91.4%)
TNFα > 8.1 pg/ml) 1.42 (0.85 ~ 2.37) 0.19 48.2% (38.7%–57.9%) 60.3% (51.2%–68.9%)
  1. Abbreviation: ESR erythrocyte sedimentation rate, hsCRP high sensitive C-reactive protein, IL-6 interleukin-6, TNFα tumor necrosis factor-α, CI confidence interval