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Table 2 Association between ESR, hsCRP, IL-6 and TNFα with disease activity at baseline in logistic regression. Results of univariate logistic regression analysis were shown in this table, which analyzed the association between ESR, hsCRP, IL-6 and TNFα with disease activity at baseline in 428 patients

From: Association between acute phase reactants, interleukin-6, tumor necrosis factor-α, and disease activity in Takayasu’s arteritis patients

 

Odds ratio (95% CI)

p value

Sensitivity (95% CI)

Specificity (95% CI)

ESR (> 20 mm/1st hour)

5.34 (3.27 ~ 8.72)

< 0.001

41.9% (34.8%–49.4%)

88.1% (83.2%–91.9%)

hsCRP (> 8 mg/L)

13.60 (8.18 ~ 22.62)

< 0.001

63.5% (56.1%–70.6%)

88.7% (83.8%–92.5%)

IL-6 (> 5.9 pg/ml)

7.75 (4.17 ~ 14.42)

< 0.001

56.1% (46.5%–65.4%)

85.8% (78.5%–91.4%)

TNFα > 8.1 pg/ml)

1.42 (0.85 ~ 2.37)

0.19

48.2% (38.7%–57.9%)

60.3% (51.2%–68.9%)

  1. Abbreviation: ESR erythrocyte sedimentation rate, hsCRP high sensitive C-reactive protein, IL-6 interleukin-6, TNFα tumor necrosis factor-α, CI confidence interval