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Table 2 Association of DAS0–4m and DAS4m with SDFR development within 7 years in ACPA-negative RA

From: Early DAS response after DMARD-start increases probability of achieving sustained DMARD-free remission in rheumatoid arthritis

  Multivariable logistics regression models
OR (95%CI) p value OR (95%CI) p value OR (95%CI) p value
Age (years) 1.01 (0.99–1.04) 0.37 1.02 (0.99–1.04) 0.38 1.02 (0.99–1.05) 0.13
Gender (male) 1.65 (0.80–3.39) 0.18 1.40 (0.66–2.97) 0.31 1.25 (0.61–2.57) 0.55
Symptom duration at diagnosis (≤ 12 weeks vs. > 12 weeks) 0.93 (0.45–1.88) 0.82 0.87 (0.42–1.79) 0.70 0.97 (0.49–1.93) 0.92
Baseline DAS   1.44 (1.00–2.08) 0.05  
DAS4 months   0.44 (0.29–0.68) < 0.01 0.51 (0.35–0.75) < 0.01
ΔDAS0–4m 0.58 (0.42–0.80) < 0.01    
  1. Legend: Multivariable logistic regression models in ACPA-negative RA (n = 184) with SDFR (yes/no) as dependent outcome variable. Multivariable analysis showed DAS levels at 4 months (DAS4 months) were as predictive of SDFR as decrease in ΔDAS0–4m, with and without incorporation of baseline DAS in the model
  2. DAS disease activity score, BL baseline, CI confidence interval