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Table 3 Prevalence of radiographic and clinical sub-phenotypes of OA in the study population, stratified by HBM status

From: Increased development of radiographic hip osteoarthritis in individuals with high bone mass: a prospective cohort study

 

All hips

HBM hips

Non-HBM hips

Total N

N (%) with sub-phenotype

Total N

N (%) with sub-phenotype

Total N

N (%) with sub-phenotype

OA (Croft > 3)

 Baseline

285

22 (7.7)

179

13 (7.3)

106

9 (8.5)

 Follow-up

275

33 (12.0)

173

24 (13.9)

102

9 (8.8)

 Incident

257

18 (7.0)

162

15 (9.3)

95

3 (3.2)

 Progressive

18

5 (27.8)

11

2 (18.2)

7

3 (42.9)

Hip replacement (identified on radiograph)

 Baseline

290

5 (1.7)

184

5 (2.7)

106

0

 Follow-up

290

15 (5.2)

184

11 (6.0)

106

4 (3.8)

 Incident

285

10 (3.5)

179

6 (3.4)

106

4 (3.8)

Osteophyte score

 Baseline

285

 

179

 

106

 

  0

 

203 (71.2)

 

126 (70.4)

 

77 (72.6)

  1–4

 

75 (26.3)

 

50 (27.9)

 

25 (23.6)

  > 5

 

7 (2.5)

 

5 (2.8)

 

4 (3.8)

 Follow-up

275

 

173

 

102

 

  0

 

161 (58.6)

 

94 (54.3)

 

67 (65.7)

  1–4

 

105 (38.2)

 

73 (42.2)

 

32 (31.4)

  > 5

 

9 (3.3)

 

6 (3.5)

 

3 (2.9)

 Delta

275

 

173

 

102

 

  < 1

 

201 (73.1)

 

121 (69.9)

 

80 (78.4)

  1

 

48 (17.5)

 

32 (18.5)

 

16 (15.7)

  > 1

 

26 (9.5)

 

20 (11.6)

 

6 (5.9)

JSN score

 Baseline

285

 

179

 

106

 

  0

 

253 (88.8)

 

160 (89.4)

 

93 (87.7)

  1–2

 

27 (9.5)

 

16 (8.9)

 

11 (10.4)

  > 3

 

5 (1.8)

 

3 (1.7)

 

2 (1.9)

 Follow-up

275

 

173

 

102

 

  0

 

241 (87.6)

 

149 (86.1)

 

92 (90.2)

  1–2

 

28 (10.2)

 

20 (11.6)

 

8 (7.8)

  > 3

 

6 (2.2)

 

4 (2.3)

 

2 (2.0)

 Delta

275

 

173

 

102

 

  < 1

 

261 (94.9)

 

161 (93.1)

 

100 (98.0)

  1

 

12 (4.4)

 

10 (5.8)

 

2 (2.0)

  > 1

 

2 (0.7)

 

2 (1.2)

 

0 (0.0)

 

All individuals

HBM individuals

Relatives without HBM

Total N

Median (IQR)

Total N

Median (IQR)

Total N

Median (IQR)

WOMAC at follow-up

 Pain

145

0 (0, 25)

92

10 (0, 35)

53

0 (0, 15)

 Function

145

3.6 (0, 25)

92

10.7 (0, 30.4)

53

0 (0, 14.3)

 

Total N

N (%)

Total N

N (%)

Total N

N (%)

Hip replacement (self-reported)

145

16 (11.0)

92

13 (14.1)

53

3 (5.7)

  1. Abbreviations: HBM high bone mass, OA osteoarthritis, JSN joint space narrowing, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index