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Table 3 Prevalence of radiographic and clinical sub-phenotypes of OA in the study population, stratified by HBM status

From: Increased development of radiographic hip osteoarthritis in individuals with high bone mass: a prospective cohort study

  All hips HBM hips Non-HBM hips
Total N N (%) with sub-phenotype Total N N (%) with sub-phenotype Total N N (%) with sub-phenotype
OA (Croft > 3)
Baseline 285 22 (7.7) 179 13 (7.3) 106 9 (8.5)
Follow-up 275 33 (12.0) 173 24 (13.9) 102 9 (8.8)
Incident 257 18 (7.0) 162 15 (9.3) 95 3 (3.2)
Progressive 18 5 (27.8) 11 2 (18.2) 7 3 (42.9)
Hip replacement (identified on radiograph)
Baseline 290 5 (1.7) 184 5 (2.7) 106 0
Follow-up 290 15 (5.2) 184 11 (6.0) 106 4 (3.8)
Incident 285 10 (3.5) 179 6 (3.4) 106 4 (3.8)
Osteophyte score
Baseline 285   179   106  
  0   203 (71.2)   126 (70.4)   77 (72.6)
  1–4   75 (26.3)   50 (27.9)   25 (23.6)
  > 5   7 (2.5)   5 (2.8)   4 (3.8)
Follow-up 275   173   102  
  0   161 (58.6)   94 (54.3)   67 (65.7)
  1–4   105 (38.2)   73 (42.2)   32 (31.4)
  > 5   9 (3.3)   6 (3.5)   3 (2.9)
Delta 275   173   102  
  < 1   201 (73.1)   121 (69.9)   80 (78.4)
  1   48 (17.5)   32 (18.5)   16 (15.7)
  > 1   26 (9.5)   20 (11.6)   6 (5.9)
JSN score
Baseline 285   179   106  
  0   253 (88.8)   160 (89.4)   93 (87.7)
  1–2   27 (9.5)   16 (8.9)   11 (10.4)
  > 3   5 (1.8)   3 (1.7)   2 (1.9)
Follow-up 275   173   102  
  0   241 (87.6)   149 (86.1)   92 (90.2)
  1–2   28 (10.2)   20 (11.6)   8 (7.8)
  > 3   6 (2.2)   4 (2.3)   2 (2.0)
Delta 275   173   102  
  < 1   261 (94.9)   161 (93.1)   100 (98.0)
  1   12 (4.4)   10 (5.8)   2 (2.0)
  > 1   2 (0.7)   2 (1.2)   0 (0.0)
  All individuals HBM individuals Relatives without HBM
Total N Median (IQR) Total N Median (IQR) Total N Median (IQR)
WOMAC at follow-up
Pain 145 0 (0, 25) 92 10 (0, 35) 53 0 (0, 15)
Function 145 3.6 (0, 25) 92 10.7 (0, 30.4) 53 0 (0, 14.3)
  Total N N (%) Total N N (%) Total N N (%)
Hip replacement (self-reported) 145 16 (11.0) 92 13 (14.1) 53 3 (5.7)
  1. Abbreviations: HBM high bone mass, OA osteoarthritis, JSN joint space narrowing, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index