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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients

Fig. 2

KPL-404 does not deplete B cells in culture. PBMCs were cultured in the presence of 10 μg/ml IgG4 isotype control or anti-CD40 Abs KPL-404, or G28-5 (16–18 h of cell culture). a Representative flow data showing the percentage of CD19+ B cells of gated live lymphocytes. b Summary data from 6 individual HD showing the percentage of live CD19+ cells in the lymphocyte population. B cell frequencies for each donor are normalized to IgG4 control. The bars represent mean and standard deviation (SD). *p < 0.05, determined by unmatched ANOVA analysis with multiple comparisons to control IgG4

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Arthritis Research & Therapy

ISSN: 1478-6362

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