Fig. 2
From: HDAC2 interacts with microRNA-503-5p to regulate SGK1 in osteoarthritis
Overexpression of miR-503-5p results in promoted proliferation and reduced apoptosis of rat primary chondrocytes. a The expression efficiency of miR-503-5p verified by RT-qPCR assay. b Apoptosis of rat primary chondrocytes after overexpression or downregulation of miR-503-5p detected by flow cytometry. c The expression of Caspase-3, Bax, and Bcl2 in primary chondrocytes after overexpression or downregulation of miR-503-5p detected by Western blot analysis. d Statistics of c. e Proliferation of rat primary chondrocytes after overexpression or downregulation of miR-503-5p detected by MTT assay. f The expression of inflammatory cytokines in rat primary chondrocytes examined by ELISA. *p < 0.05. Measurement data were expressed as mean ± standard deviation. Comparisons among multiple groups were conducted by one-way ANOVA with Tukey’s post hoc test. The experiment was repeated three times