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Table 3 Results of multiple regression analyses of each variable and JKOM pain score in each model

From: Obesity with radiological changes or depression was associated with worse knee outcome in general population: a cluster analysis in the Nagahama study

 

Full model

Reduced model 1

Reduced model 2

Reduced model 3

Standardized beta (95% CI)

P value

Standardized beta (95% CI)

P value

Standardized beta (95% CI)

P value

Standardized beta (95% CI)

P value

Age

0.096 (0.052–0.129)

< 0.0001

0.106 (0.065–0.134)

< 0.0001

0.105 (0.065–0.133)

< 0.0001

–

–

Sex

− 0.038 (− 0.0543– 0.156)

0.2772

–

–

–

–

–

–

BMI

0.136 (0.146–0.284)

< 0.0001

0.128 (0.139–0.26)

< 0.0001

0.124 (0.135–0.256)

< 0.0001

0.123 (0.133–0.255)

< 0.0001

K/L grade

0.344 (1.999–2.509)

< 0.0001

0.340 (1.977–2.460)

< 0.0001

0.340 (1.982–2.465)

< 0.0001

0.359 (2.104–2.583)

< 0.0001

Muscle mass of lower extremity

− 0.020 (− 0.309–0.168)

0.5634

–

–

–

–

–

–

BMD

− 0.030 (− 0.346–0.390)

0.1187

− 0.025 (− 0.312–0.057)

0.1763

− 0.026 (− 0.314–0.054)

0.1660

− 0.038 (− 0.376 to − 0.008)

0.0412

Depressive symptom

0.068 (0.274–0.875)

0.0002

0.067 (0.268–0.867)

0.0002

0.067 (0.272–0.870)

0.0002

0.064 (0.241–0.843)

0.0004

hs-CRP

0.033 (− 0.055–0.749)

0.091

0.033 (− 0.050–0.743)

0.0864

0.030 (− 0.071–0.704)

0.1094

0.037 (0.003–0.781)

0.0484

Hb-A1c

− 0.001 (− 0.367–0.350)

0.9628

− 0.001 (− 0.349–0.365)

0.9649

–

–

–

–

HDL-cholesterol

0.010 (− 0.009–0.015)

0.6405

0.015 (− 0.007–0.015)

0.4626

–

–

–

–

LDL-cholesterol

− 0.018 (− 0.009–0.015)

0.3365

–

–

–

–

–

–

Triglyceride

− 0.014 (− 0.005–0.003)

0.5066

–

–

–

–

–

–

Uric acid

− 0.012 (− 0.212–0.119)

0.5814

–

–

–

–

–

–

  1. Reduced model 1: Selected the variable which showed a statistically significant correlation with JKOM pain. Reduced model 2: Selected the variable by stepwise method. Reduced model 3: Excluded age from reduced model 2
  2. Variables in bold indicate statistically significant results
  3. BMI body mass index, K/L Kellgren/Lawrence, BMD bone mineral density, hs-CRP high-sensitivity C-reactive protein, HbA1c hemoglobin A1c