Patients with PMR symptoms at diagnosis (n = 32) | Patients without PMR symptoms at diagnosis (n = 28) | |||
---|---|---|---|---|
Before TCZ initiation | After TCZ initiation | Before TCZ initiation | After TCZ initiation | |
Follow-up time, median (IQR), years | 0.7 (0.2–1.9) | 0.6 (0.4–1.6) | 0.6 (0.2–1.4) | 0.5 (0.3–1.5) |
Rate of flares per year* | 1.6 (0.8–3.2) | |||
Rate (95% CI) | 1.3 (0.8–2.1) | 0.5 (0.3–1.1) | 0.7 (0.3–1.7) | |
Rate ratio (95% CI) | 0.4 (0.2–0.7) | 0.4 (0.2–0.9) | ||
p value | 0.003 | 0.03 | ||
Patients with ≥ 1 flare, n (%) | 24 (75.0) | 11 (34.4) | 19 (67.9) | 7 (25.0) |
With PMR symptoms† | 21 (65.6) | 8 (25.0) | 4 (14.3) | 2 (7.1) |
Without PMR symptoms† | 3 (9.4) | 3 (9.4) | 15 (53.6) | 5 (17.9) |
Total no. of flares | 60 | 23 | 42 | 14 |
With PMR symptoms, n (%)† | 50 (83.3) | 18 (78.3) | 7 (16.7) | 3 (21.4) |
Without PMR symptoms, n (%)† | 10 (16.7) | 5 (21.7) | 35 (83.3) | 11 (78.6) |