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Table 3 Univariate and multivariate analyses for predictors of persistence with initial biologic at 12 years

From: Long-term remission and biologic persistence rates: 12-year real-world data

 

Univariate

Multivariate

p

OR (95% CI)

p

Persistence at 1 year

0.011

4.28 (1.28–14.38)

0.019

One-year low-disease activity

< 0.001

3.90 (1.05–14.53)

0.042

Smoker/ex-smoker at baseline

0.055

0.39 (0.14–1.10)

0.074

Completed university

0.033

1.84 (0.54–6.27)

0.333

Etanercept at baseline

0.020

1.51 (0.56–4.07)

0.411

Baseline alcohol use

0.135

1.37 (0.47–4.04)

0.565

Infliximab at baseline

0.156

0.50 (0.05–5.00)

0.557

Male gender

0.061

0.75 (0.24–2.38)

0.623

Finished secondary school

0.010

0.85 (0.26–2.78)

0.784

Remission at 1 year

0.002

0.87 (0.27–2.86)

0.823

Baseline methotrexate use

0.084

1.07 (0.40–2.89)

0.897

Age > 50 years

0.797

0.97 (0.32–2.90)

0.950