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Table 3 Univariate and multivariate analyses for predictors of persistence with initial biologic at 12 years

From: Long-term remission and biologic persistence rates: 12-year real-world data

  Univariate Multivariate
p OR (95% CI) p
Persistence at 1 year 0.011 4.28 (1.28–14.38) 0.019
One-year low-disease activity < 0.001 3.90 (1.05–14.53) 0.042
Smoker/ex-smoker at baseline 0.055 0.39 (0.14–1.10) 0.074
Completed university 0.033 1.84 (0.54–6.27) 0.333
Etanercept at baseline 0.020 1.51 (0.56–4.07) 0.411
Baseline alcohol use 0.135 1.37 (0.47–4.04) 0.565
Infliximab at baseline 0.156 0.50 (0.05–5.00) 0.557
Male gender 0.061 0.75 (0.24–2.38) 0.623
Finished secondary school 0.010 0.85 (0.26–2.78) 0.784
Remission at 1 year 0.002 0.87 (0.27–2.86) 0.823
Baseline methotrexate use 0.084 1.07 (0.40–2.89) 0.897
Age > 50 years 0.797 0.97 (0.32–2.90) 0.950