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Table 3 Comparison of histological scores at the 6th and 12th weeks after operation (n = 12)

From: Silk fibroin hydrogel scaffolds incorporated with chitosan nanoparticles repair articular cartilage defects by regulating TGF-β1 and BMP-2

Time point

Control

CS/SF

TGFβ1

BMP2

TGFβ1/BMP2

TGF-β1@CS/BMP-2@SF

The 6th week

11.00 ± 1.28

8.58 ± 1.08*

7.25 ± 1.96*

8.08 ± 1.31*

5.58 ± 1.24*&

5.67 ± 0.78*#

The 12th week

9.92 ± 1.08

5.92 ± 0.79*

4.75 ± 1.22*

5.42 ± 1.98*

3.17 ± 1.11*&

2.33 ± 0.49*#

  1. The results were measurement data and expressed as mean ± standard deviation. Data comparison among multiple groups was analyzed by one-way ANOVA, followed by Tukey’s post hoc test. The experiment was repeated 3 times independently
  2. *p < 0.05 vs. the control group at the same time
  3. #p < 0.05 vs. the CS/SF group at the same time
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Arthritis Research & Therapy

ISSN: 1478-6362

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