Table 4 Minimum acceptable benefit for changes in attribute levels
Attribute | Change | Minimum acceptable benefit in percentage | ||
|---|---|---|---|---|
Class 1 | Class 2 | Class 3 | ||
Probability of mild short-term side effects | Moving from 0.1 to 10% | 2.5 | 27.0 | 11.0 |
Moving from 0.1 to 1% | 1.3 | – | 1.5 | |
Moving from 1 to 10% | 1.3 | 35.0 | 9.5 | |
Probability of side effects changing appearance | Moving from 0.1 to 10% | 7.3 | 34.1 | 38.8 |
Moving from 0.1 to 1% | – | 10.0 | 12.0 | |
Moving from 1 to 10% | 7.6 | 24.0 | 26.8 | |
Probability of psychological side effects | Moving from 0.1 to 10% | 9.3 | 75.0 | 65.3 |
Moving from 0.1 to 1% | – | 62.0 | 8.5 | |
Moving from 1 to 10% | 9.3 | 13.0 | 56.8 | |
Probability of severe side effects | Moving from 0.1 to 10% | 14.6 | 21.0 | 91.3 |
Moving from 0.1 to 1% | – | 8.0 | 18.8 | |
Moving from 1 to 10% | 21.4 | 13.0 | 71.5 | |