|
EULAR (CRP) response, n (%)
|
|
Week 2
|
|
Good response
|
22 (6.8)
|
13 (4.0)
|
|
Moderate response
|
154 (47.5)
|
139 (42.9)
|
|
Week 4
|
|
Good response
|
72 (22.2)
|
68 (21.0)
|
|
Moderate response
|
162 (50.0)
|
167 (51.5)
|
|
Week 8
|
|
Good response
|
133 (41.0)
|
123 (38.0)
|
|
Moderate response
|
143 (44.1)
|
144 (44.4)
|
|
Week 12
|
|
Good response
|
162 (50.0)
|
165 (50.9)
|
|
Moderate response
|
131 (40.4)
|
124 (38.3)
|
|
Week 16
|
|
Good response
|
181 (55.9)
|
174 (53.7)
|
|
Moderate response
|
112 (34.6)
|
109 (33.6)
|
|
Week 20
|
|
Good response
|
202 (62.3)
|
201 (62.0)
|
|
Moderate response
|
91 (28.1)
|
87 (26.9)
|
|
Week 24
|
|
Good response
|
208 (64.2)
|
208 (64.2)
|
|
Moderate response
|
86 (26.5)
|
81 (25.0)
|
|
CDAI remission rate, n (%)
|
|
Week 2
|
2 (0.6)
|
2 (0.6)
|
|
Week 4
|
11 (3.4)
|
11 (3.4)
|
|
Week 8
|
21 (6.5)
|
24 (7.4)
|
|
Week 12
|
47 (14.5)
|
42 (13.0)
|
|
Week 16
|
51 (15.7)
|
63 (19.4)
|
|
Week 20
|
69 (21.3)
|
85 (26.2)
|
|
Week 24
|
82 (25.3)
|
86 (26.5)
|
|
SDAI remission rate, n (%)
|
|
Week 2
|
2 (0.6)
|
2 (0.6)
|
|
Week 4
|
12 (3.7)
|
12 (3.7)
|
|
Week 8
|
22 (6.8)
|
22 (6.8)
|
|
Week 12
|
47 (14.5)
|
44 (13.6)
|
|
Week 16
|
53 (16.4)
|
65 (20.1)
|
|
Week 20
|
69 (21.3)
|
87 (26.9)
|
|
Week 24
|
86 (26.5)
|
93 (28.7)
|
|
DAS28 (CRP) remission rate, n (%)
|
|
Week 2
|
11 (3.4)
|
10 (3.1)
|
|
Week 4
|
32 (9.9)
|
38 (11.7)
|
|
Week 8
|
67 (20.7)
|
68 (21.0)
|
|
Week 12
|
109 (33.6)
|
107 (33.0)
|
|
Week 16
|
128 (39.5)
|
118 (36.4)
|
|
Week 20
|
150 (46.3)
|
146 (45.1)
|
|
Week 24
|
158 (48.8)
|
157 (48.5)
|
|
Boolean remission rate, n (%)
|
|
Week 2
|
2 (0.6)
|
2 (0.6)
|
|
Week 4
|
9 (2.8)
|
10 (3.1)
|
|
Week 8
|
17 (5.2)
|
17 (5.2)
|
|
Week 12
|
32 (9.9)
|
33 (10.2)
|
|
Week 16
|
40 (12.3)
|
56 (17.3)
|
|
Week 20
|
56 (17.3)
|
66 (20.4)
|
|
Week 24
|
58 (17.9)
|
68 (21.0)
|
