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Table 3 miR-143 haplotype distribution

From: Association study between immune-related miRNAs and mixed connective tissue disease

rs353299

rs353291

rs713147

rs353298

p value

Hap-Freq

Healthy control

Hap-Freq MCTD

T

T

T

G

< 0.0001

0.14

0.31

C

C

T

A

0.002

0.11

0.23

C

T

T

G

0.004

0.07

0.01

T

T

A

A

0.008

0.04

NA

T

C

T

A

0.009

0.06

0.01

T

T

T

A

0.02

0.05

0.01

C

C

T

G

0.16

0.04

0.02

  1. MCTD mixed connective tissue diseases, Hap-Freq haplotype frequency; 2nMCTD-210 2nControl-470 Bonferroni correction was used to adjust the significance of p value. p value < 0.003 was considered as significant