Table 6 Association between miR-143 rs353298 A/G polymorphism and MCTD clinical parameters

 miR-143 rs353298 A/G

Model

p

OR

  Genotype

AA

AG

GG

GG + AG vs AA

0.49

1.83

0.54

6.26

   Pericarditis/pleuritis

4 (11.11)

5 (12)

6 (35)

AA + AG vs GG

0.04

4.18

1.24

14.07

   Without pericarditis/pleuritis

32 (88.89)

37 (88)

11 (65)

GG + AA vs AG

0.52

0.58

0.18

1.85

  Allele

A

G

GG vs AA

0.04

4.36

1.04

18.39

   Pericarditis/pleuritis

13 (11)

17 (22)

AG vs AA

0.9129

1.08

0.27

4.37

   Without pericarditis/pleuritis

101 (89)

59 (78)

G vs A

0.05

2.24

1.02

4.93

 miR-143 rs353298 A/G

Model

p

OR

  Genotype

AA

AG

GG

GG + AG vs AA

0.87

0.84

0.35

2.01

   Scleroderma

13 (36.11)

17 (40)

2 (12)

AA + AG vs GG

0.05

0.21

0.05

1

   Without scleroderma

23 (63.89)

25 (60)

15 (88)

GG + AA vs AG

0.30

1.72

0.73

4.06

  Allele

A

G

GG vs AA

0.0814

0.24

0.05

1.2

   Scleroderma

43 (38)

21 (28)

AG vs AA

0.6929

1.2

0.48

3.01

   Without scleroderma

71 (62)

55 (72)

A vs G

0.1509

0.63

0.34

1.18