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Table 7 MCTD clinical parameters significantly associated with miR-143 rs353291 T/C

From: Association study between immune-related miRNAs and mixed connective tissue disease

Pericarditis/pleuritis

miR-143 rs353291 T/C

n (%)

Model

p

OR

95% CI

Genotype

TT

TC

CC

CC + TC vs TT

0.33

0.54

0.18

1.59

 Pericarditis/pleuritis

8 (22.22)

3 (7)

5 (28)

TT + TC vs CC

0.18

2.34

0.7

7.88

 Without pericarditis/pleuritis

28 (77.78)

39 (93)

13 (72)

CC + TT vs TC

0.03

0.24

0.06

0.92

Allele

T

C

 

CC vs TT

0.6532

1.35

0.37

4.92

 Pericarditis/pleuritis

19 (17)

13 (17)

 

TC vs TT

0.0687

0.27

0.07

1.11

 Without pericarditis/pleuritis

95 (83)

65 (83)

 

T vs C

1

1

0.46

2.17

  1. n number of patients with clinical information; p value < 0.05 is considered significant, indicated in bold; p value obtained from χ2 or Fisher exact test