Fig. 6

Logistic regression analysis for selected biomarker candidates in healthy controls and rheumatoid arthritis (RA) patients. Predictive accuracy of single (a) and the four biomarker candidates (b). Receiver operating characteristic curve (ROC) analysis of single (c) and four biomarker candidates (d) was performed. The number of healthy controls and RA patients was 251 and 230, respectively. The plots indicate individual protein abundance in each group. Data are presented as mean ± SEM values. Independent samples t tests were used to determine the statistical significance