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Table 1 Characteristics of the study population

From: Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis

 

Total study population

Surface marker/MACSPlex

ICS

Number of patients, n

40

31

9

Gender, n (%)

 Male

11 (27.5%)

10 (32.2%)

1 (11.1%)

 Female

29 (72.5%)

21 (67.8%)

8 (88.9%)

Age at surgery, years

41.7 ± 14.3

41.3 ± 14.1

43 ± 14.9

 Mean ± SD (IQR)

(28.4–51.2)

(28–52.5)

(30–47)

Operation side, n (%)

 Right

17 (42.5%)

14 (45.2%)

3 (33.3%)

 Left

23 (57.5%)

17 (54.8%)

6 (66.6%)

BMI, kg/m2

27.9 ± 6.4

28.5 ± 7.2

25.7 ± 4.4

 Mean ± SD (IQR)

(23.2–30.3)

(23.9–31.4)

(22.6–29.4)

Leucocytes/nl

7.01 ± 1.9

7.3 ± 1.9

6.38 ± 1.8

 Mean ± SD (IQR)

(5.9–7.9)

(5.9–7.94)

(5.8–7.9)

C-reactive protein, mg/dl

3.3 ± 1.9

3.2 ± 2.2

3.4 ± 1.1

 Mean ± SD (IQR)

(2–4)

(2.0–3.85)

(2–4)

Time from onset of symptoms/trauma to operation in months, n (%)

 1–3

2 (5%)

2 (6.4%)

0

 4–6

16 (40%)

13 (42%)

3 (33.3%)

 7–9

5 (12.5%)

4 (12.9%)

1 (11.1%)

 10–12

7 (17.5%)

4 (12.9%)

3 (33.3%)

 > 12

10 (25%)

8 (25.8%)

2 (22.2%)

ICRS grade

 I–IV in ≥ 2 compartments

2 (5%)

2 (6.5%)

0

 II–IV in 1 compartment

38 (95%)

29 (93.5%)

9 (100%)

Pathology, n (%)

 Meniscus tear

16 (40%)

14/31 (45.1%)

2/9 (22.2%)

 ACL tear

2 (5%)

2/31 (6.5%)

0/9

 Localized cartilage damage

22 (55%)

15/31 (48.4%)

7/9 (77.7%)

  1. Demographic and clinical parameters of the study population are shown. Values are shown as mean ± standard deviation (range) or as number (p%). ICRS grade was evaluated by independent surgeons intraoperatively
  2. IQR interquartile range, BMI body mass index, K & L score Kellgren and Lawrence score (radiological score), ICRS grade International Cartilage Repair Society grade (arthroscopical grading), ACL anterior cruciate ligament