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Table 1 Normalized intensity comparison of differentially expressed microRNAs between SSc patients and HCs

From: MicroRNA-320a: an important regulator in the fibrotic process in interstitial lung disease of systemic sclerosis

MicroRNA

Log2 [fold change]

t test p value

Expression

hsa-miR-3682-3p

1.068379

0.013*

Upregulation

hsa-miR-4271

1.100022

0.096

Upregulation

hsa-miR-4481

1.381003

0.060

Upregulation

hsa-miR-4498

0.87481

0.004**

Upregulation

hsa-miR-4653-3p

1.788449

0.052

Upregulation

hsa-miR-4706

1.087915

0.046*

Upregulation

hsa-miR-4764-5p

0.776084

0.045*

Upregulation

hsa-miR-1207-5p

− 0.889822

0.460

Downregulation

hsa-miR-29b-2-5p

− 0.70392

0.008**

Downregulation

hsa-miR-320a

− 0.976112

0.033*

Downregulation

hsa-miR-320b

− 0.945275

0.002**

Downregulation

hsa-miR-320c

− 0.946686

0.034*

Downregulation

hsa-miR-320d

− 0.742298

0.035*

Downregulation

hsa-miR-320e

− 0.651448

0.020*

Downregulation

hsa-miR-324-5p

− 0.911236

0.060

Downregulation

hsa-miR-362-5p

− 0.601584

0.009**

Downregulation

hsa-miR-363-5p

− 0.924108

0.105

Downregulation

hsa-miR-3656

− 0.766701

0.058

Downregulation

hsa-miR-423-3p

− 0.792722

0.038*

Downregulation

hsa-miR-423-5p

− 1.155325

0.047*

Downregulation

hsa-miR-4284

− 0.69124

0.042*

Downregulation

hsa-miR-4508

− 0.653161

0.406

Downregulation

hsa-miR-4516

− 0.600174

0.300

Downregulation

hsa-miR-500a-3p

− 0.627692

0.003**

Downregulation

hsa-miR-652-3p

− 1.043636

0.061

Downregulation

  1. Differentially expressed microRNAs were compared by both fold change test and t test
  2. *p value < 0.05
  3. **p value < 0.01