Skip to main content

Table 3 Univariable GEE, longitudinal associations of SLE clinical indicators with SLEQOL and SF36 survey scores

From: Comparison of performance of specific (SLEQOL) and generic (SF36) health-related quality of life questionnaires and their associations with disease status of systemic lupus erythematosus: a longitudinal study

 HRQoL survey outcomes
SLEQOL-total scoreSF36-PCSSF36-MCS
Mean (95% CI)RC (95% CI), p valueMean (95% CI)RC (95% CI), p valueMean (95% CI)RC (95% CI), p value
LLDAS status
 Not in LLDAS85.7 (84.4, 86.9)Ref.46.2 (45.4, 47.0)Ref.48.1 (47.2, 48.9)Ref.
 In LLDAS88.7 (87.6, 89.9)3.0 (2.0, 4.0), p < 0.0147.7 (46.9, 48.5)1.5 (0.9, 2.1), p < 0.0149.7 (48.8, 50.6)1.6 (0.9, 2.4), p < 0.01
SLEDAI-2K
 SLEDAI-2K ≤ 488.0 (86.9, 89.2)Ref.47.4 (46.7, 48.2)Ref.49.2 (48.4, 50.0)Ref.
 SLEDAI-2K > 484.8 (83.4, 86.3)− 3.2 (− 4.4, − 2.0), p < 0.0145.6 (44.6, 46.6)− 1.8 (− 2.6, − 1.0), p < 0.0147.8 (46.9, 48.8)− 1.4 (− 2.2, − 0.5), p < 0.01
Flare
 Absent87.4 (86.2, 88.5)Ref.47.2 (46.5, 47.9)Ref.48.9 (48.1, 49.8)Ref.
 Present85.7 (84.1, 87.3)− 1.7 (− 2.8, − 0.5), p < 0.0145.2 (44.2, 46.2)− 2.0 (− 2.6, − 1.3), p < 0.0148.3 (47.3, 49.4)− 0.6 (− 1.4, 0.2), p = 0.15
Organ damage
 Absent88.4 (87.0, 89.8)Ref.48.5 (47.7, 49.4)Ref.48.8 (47.8, 49.8)Ref.
 Present85.8 (84.2, 87.3)− 2.6 (− 4.5, − .08), p < 0.0145.3 (44.3, 46.3)− 3.2 (− 4.4, − 2.1), p < 0.0148.8 (47.7, 49.9)0.0 (− 1.4, 1.4), p = 0.9
  1. RC = regression coefficient = mean difference