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Table 4 Multivariable, longitudinal associations of SLE clinical indicators with SLEQOL and SF36 survey scores

From: Comparison of performance of specific (SLEQOL) and generic (SF36) health-related quality of life questionnaires and their associations with disease status of systemic lupus erythematosus: a longitudinal study

 HRQoL survey outcomes
SLEQOL-total score, RC* (95% CI), p valueSF36-PCS, RC* (95% CI), p valueSF36-MCS, RC* (95% CI), p value
In LLDAS3.01 (2.1, 4.1), p < 0.0011.51 (1.0, 2.1), p < 0.0011.61 (0.9, 2.4), p < 0.001
SLEDAI-2K > 4− 3.122 (− 4.44, − 1.79), p < 0.01− 1.523 (− 2.37, − 0.68), p < 0.01− 1.364 (− 2.18, − 0.54), p < 0.001
Flare− 0.585 (− 1.83, 0.66), p = 0.4− 1.506 (− 2.20, − 0.80), p < 0.01
Organ damage− 2.537 (− 4.33, − 0.74), p = 0.01− 2.668 (− 3.72, − 1.59), p < 0.01
  1. RC* = regression coefficient = mean difference compared to patients without clinical indicators
  2. 1LLDAS associations adjusted for education level. SLEDAI-2K associations adjusted for 2flare, organ damage, and education level; 3flare, organ damage, education level, and age at enrolment; 4disease duration and education level. Flare associations adjusted for 5SLEDAI-2K > 4, organ damage, and education level, and 6SLEDAI-2K > 4, organ damage, education level, and age at enrolment. Organ damage associations adjusted for 7flare, SLEDAI-2K > 4, and education level, and 8SLEDAI-2K > 4, flare, organ damage, education level, and age at enrolment