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Table 2 Treatments and disease characteristics of ESPOIR RA patients 1-year post-inclusion

From: Reduced progression of bone erosion in cytomegalovirus seropositive rheumatoid arthritis patients

 All RA patients (n = 487)HCMV seropositive RA patients (n = 273) (56%)HCMV seronegative RA patients (n = 214) (44%)p (HCMV+ versus HCMV−)
Patients with DMARD, n (%)417/458 (91.05)237/262 (90.5)180/196 (91.8)0.6090
Use of csDMARD, n (%)376/458 (82.10)210/262 (80.15)166/196 (84.70)0.2100
Use of bDMARD, n (%)41/458 (8.95)27/262 (10.31)14/196 (7.14)0.2410
Delay between inclusion and first DMARD (months), median (IQR)0.38 (0.03–1.20)0.39 (0.03–1.22)0.36 (0.07–1.38)0.5225
Patients with glucocorticoids at baseline, n (%)0 (0)0 (0)0 (0)
Cumulated dose of glucocorticoids between inclusion and 1 year in milligram, median (IQR)210 (0–2120)646 (0–2217)100 (0–1935)0.1393
Total Sharp score (mTSS), median (IQR)4 (1–10)4 (1–9)4 (1–10)0.8913
Delta total Sharp score (0–1 year), mean (SD)*1.70 (4.49)1.29 (3.38)2.22 (5.57)0.0238
Delta total Sharp score (0–1 year), median (IQR)0 (0–1) p95 = 110 (0–1) p95 = 90 (0–2) p95 = 130.0349
  OR [95% CI] = 0.623 [0.464–1.005]0.0540
Delta Sharp total score (0–1 year) > 1, n (%)*103 (21.2)47 (17.2)*56 (26.3)0.0151
  OR [95% CI] = 0.583 [0.367–0.925]0.0151
Joint space narrowing Sharp score (NSS), median (IQR)1 (0–5)1 (0–5)1 (0–4)0.9121
Delta joint space narrowing Sharp score (0–1 year), mean (SD)0.26 (1.16)0.24 (1.17)0.29 (1.14)0.6992
Delta joint space narrowing Sharp score (0–1 year), median (IQR)0 (0–0) p95 = 20 (0–0) p95 = 10 (0–0) p95 = 20.4129
  OR [95% CI] = 0.763 [0.378–1.541]0.4129
Joint space narrowing Sharp score (0–1 year), Δ > 1, n (%)26/486 (5.3)13 (4.8)13 (6.1)0.5140
  OR [95% CI] = 0.769 [0.321–1.846]0.5140
Erosion Sharp score (ESS), median (IQR)2 (0–5)2 (0–5)2 (0–6)0.9588
Delta erosion Sharp score (0–1 year), mean (SD)*1.43 (3.82)1.05 (2.63)1.93 (4.90)0.0112
Delta erosion Sharp score (0–1 year), median (IQR)*0 (0–1) p95 = 90 (0–1) p95 = 8*0 (0–2) p95 = 120.0172
  OR [95% CI] = 0.637 [0.432–0.939]0.0230
Erosion Sharp score (0–1 year), Δ > 1, n (%)*98 (20.1)44 (16.1)*54 (25.2)0.0128
  OR [95% CI] = 0.569 [0.355–0.911]0.0128
  1. * p < 0.05