Table 4 Adjusted hazard ratios (aHR) and 95% confidence intervals (CI) for comorbid conditions, individually, on modeled transition states, over the full follow-up period, by race
Strata | Type of transition | Obesity (vs no obesity)1 | DM (vs no DM)1 | CVD (vs no CVD)1 |
|---|---|---|---|---|
n (vs n) for transitions | ||||
aHR (95% CI) | ||||
White | Development of rHOA | |||
No rHOA/symptoms (A) to rHOA (B) | 45 (vs 88) | 18 (vs 115) | 46 (vs 87) | |
0.75 (0.51, 1.11) | 0.93 (0.48, 1.80) | 1.49 (0.99, 2.24) | ||
Symptoms only (C) to sxHOA (D) | 31 (vs 22) | 12 (vs 41) | 33 (vs 20) | |
1.48 (0.89, 2.44) | 1.16 (0.61, 2.23) | 1.02 (0.58, 1.77) | ||
Development of symptoms | ||||
No rHOA/symptoms (A) to symptoms only (C) | 107 (vs 107) | 46 (vs 168) | 76 (vs 138) | |
1.46 (1.06, 2.00) | 1.20 (0.75, 1.90) | 1.31 (0.91, 1.89) | ||
rHOA (B) to sxHOA (D) | 65 (vs 72) | 25 (vs 112) | 57 (vs 80) | |
0.88 (0.65, 1.54) | 0.94 (0.47, 1.87) | 1.36 (0.84, 2.21) | ||
Resolution of symptoms | ||||
Symptoms only (C) to no rHOA/symptoms (A) | 100 (vs 99) | 38 (vs 161) | 69 (vs 130) | |
1.03 (0.75, 1.43) | 0.68 (0.40, 1.17) | 0.58 (0.39, 0.85) | ||
sxHOA (D) to rHOA (B) | 73 (vs 59) | 29 (vs 103) | 55 (vs 77) | |
0.87 (0.57, 1.38) | 0.58 (0.31, 1.06) | 0.87 (0.54, 1.39) | ||
Black | Development of rHOA | |||
No rHOA/symptoms (A) to rHOA (B) | 37 (vs 28) | 21 (vs 44) | 23 (vs 42) | |
1.11 (0.69, 1.78) | 1.10 (0.59, 2.06) | 1.17 (0.69, 1.97) | ||
Symptoms only (C) to sxHOA (D) | 7 (vs 5) | 6 (vs 6) | 8 (vs 4) | |
1.09 (0.32, 3.71) | 3.57 (1.10, 11.7) | 1.22 (0.36, 4.04) | ||
Development of symptoms | ||||
No rHOA/symptoms (A) to symptoms only (C) | 49 (vs 26) | 18 (vs 57) | 32 (vs 43) | |
1.00 (0.59, 1.72) | 0.79 (0.40, 1.57) | 1.19 (0.66, 2.17) | ||
rHOA (B) to sxHOA (D) | 22 (vs 13) | 14 (vs 21) | 14 (vs 21) | |
0.69 (0.32, 1.46) | 2.09 (0.97, 4.54) | 0.63 (0.27, 1.49) | ||
Resolution of symptoms | ||||
Symptoms only (C) to no rHOA/symptoms (A) | 64 (vs 38) | 29 (vs 73) | 38 (vs 64) | |
0.66 (0.42, 1.04) | 0.77 (0.46, 1.31) | 0.70 (0.43, 1.13) | ||
sxHOA (D) to rHOA (B) | 31 (vs 11) | 9 (vs 33) | 17 (vs 25) | |
0.69 (0.35, 1.39) | 0.91 (0.37, 2.24) | 0.52 (0.25, 1.09) | ||