Fig. 3
From: Tumour necrosis factor alpha promotes secretion of 14-3-3η by inducing necroptosis in macrophages
PAD4 is localized in CD68+ cells and CD55+ cells in the RA synovium. Synovium (n = 3) specimens of patients with RA were assessed by IF using primary antibodies against PAD4 and 14-3-3η (a), PAD4 and CD68 (b), 14-3-3η and CD55 (c), or PAD4 and CD55 (d) and by FITC or rhodamine-labelled secondary antibodies. Representative images from three independent experiments are shown. Scale bar, 50 μm