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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Aryl hydrocarbon receptor signals attenuate lung fibrosis in the bleomycin-induced mouse model for pulmonary fibrosis through increase of regulatory T cells

Fig. 3

FICZ did not affect total number of several lymphocyte subsets in the lung. BLM at 0.06 units/animal was intratracheally administered with (denoted as FICZ) or without FICZ (vehicle). Flow cytometry was used to examine single-cell suspensions extracted from lung tissues stained with anti-mouse CD45, CD3, CD4, γδ, CD8, B220, NK-1.1, and viability dye 1 week after BLM administration. Total number of CD3+ T cells (a), CD3+CD4+ T cells (b), CD3+CD8+ T cells (c), CD3+γδ+ T cells (d), CD3B220NK1.1+ NK cells (e), and B220+ B cells (f) was compared between the two groups. n = 5 in each group using Mann-Whitney test

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