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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis

Fig. 3

Patients with stable LN have higher numbers of circulating CD117+ ILCs and cytokine-producing ILCs. a Differences in clinical parameters of those with active and stable LN. b Changes in total ILCs, CD117+ ILCs, CRTH2+ ILCs, and CD117/CRTH2 ILCs are shown as min. to max. Box-and-whisker plots (line represents the median). c, d Changes in IFN-γ+, IL-13+, IL-17A+, PD-1+ ILCs, and cytokine-negative ILCs in PBMC from those with active LN (n = 12) or stable LN (n = 10). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 (Student’s t test). ##P < 0.01 (Mann-Whitney test)

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