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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: The relationship between synovial inflammation, structural pathology, and pain in post-traumatic osteoarthritis: differential effect of stem cell and hyaluronan treatment

Fig. 3

Histology scoring of OA pathology at different 4, 8 and 12 weeks post-DMM from mouse OA joints (box plot showing 25–75% percentile [box], median [line in the box], and data range [whiskers]). Maximal scores (single highest pathology score per joint) and summed scores (sum of scores from all the slides per joint) are presented. a Cartilage proteoglycan loss. b Cartilage structural damage. c Posterior synovitis. d Bone pathology. Brackets indicate P < 0.05 between treatments at the same time point. *P < 0.05 compared with the same treatment group 4-week scores. #P < 0.05 compared with the same treatment group 8-week scores

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