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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?

Fig. 3

TGFβ regulates the expression of TGFβ-activating integrins in SSc monocytes. CD14+ monocytes were isolated using positive selection from the PBMC fraction of fresh blood and stimulated for 0, 1, 2, 4, 6, and 16 h with 5 ng/ml rhTGFβ1 or the TGFβ receptor inhibitor SB-505124 at a dose of 5 μM or vehicle control (DMSO) while seeded on plastic. At indicated time points, RNA was isolated and gene expression was measured

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